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Absorption | Importance for Supplements & Effectiveness

GLOSSARY

J.Simeone | Biohack Health Now Author

7/17/20242 min read

Image: Absorption | Glossary |

Absorption

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Absorption refers to the process by which substances are taken up into the body through the skin, intestines, or other tissues. In the context of supplements and medications, absorption specifically refers to how well and how quickly a substance enters the bloodstream after being administered.

Absorption is a crucial aspect of pharmacology and nutrition, as it determines the effectiveness of a supplement or drug. Several factors can influence absorption, including the form of the substance, the presence of other foods or drugs, and the health of the digestive system.

  • Oral Absorption: This occurs when a substance is ingested and passes through the digestive system before entering the bloodstream. Factors like stomach acidity, enzyme activity, and intestinal health can affect oral absorption.

  • Topical Absorption: This happens when a substance is applied to the skin and penetrates through the layers of the skin into the bloodstream. This method is often used for creams, lotions, and transdermal patches.

  • Sublingual Absorption: Involves placing a substance under the tongue, where it dissolves and is absorbed directly into the bloodstream through the mucous membranes.

  • Inhalation Absorption: This occurs when a substance is breathed in and absorbed through the lungs into the bloodstream. This method is common for drugs administered via inhalers or nebulizers.

  1. Bioavailability: The proportion of a substance that enters the bloodstream and is available for use or storage in the body. Higher bioavailability means better absorption.

  2. Solubility: Water-soluble substances are generally absorbed more easily than fat-soluble ones.

  3. Chemical Stability: Substances that are chemically stable in the digestive system are absorbed more effectively.

  4. Presence of Other Substances: Certain foods, drinks, or medications can enhance or inhibit the absorption of a substance. For example, Vitamin C can enhance iron absorption, while calcium can inhibit the absorption of certain medications.

Importance of Absorption:

Understanding absorption is vital for determining the dosage and effectiveness of supplements and medications. Poor absorption can lead to ineffective treatment, while enhanced absorption can improve therapeutic outcomes.

References

  • "Absorption (pharmacology)." Wikipedia, Absorption

  • "Factors Affecting Drug Absorption." Merck Manuals, Drug Absorption

  • "Bioavailability and Absorption of Nutritional Supplements." NIH, Bioavailability

Definition:

Detailed Explanation:

Types of Absorption:

Factors affecting Absorption:

Example in Supplements

TrueScience Liquid Collagen is formulated to optimize absorption, ensuring that the collagen peptides are readily available in the bloodstream to support skin hydration, elasticity, and joint health. The liquid form enhances bioavailability, making it more effective than some powdered or tablet forms of collagen supplements.